At least 21 people were killed after ferocious storms and tornadoes tore down buildings and causing mass destruction in the southern United States.
Hundreds others were injured.
Most of the deaths occurred on Sunday after tornadoes hit Arkansas and other states.
Monday’s twister in Tupelo, one of several to tear across Mississippi, damaged hundreds of homes and businesses, downed power lines and tore up trees, the National Weather Service said.
After the Monday’s tornado in Tulopo, officials imposed an 8 p.m. (0100 GMT) curfew and in some residential areas were closed off as emergency crews checked downed power lines and gas leaks.
The storm system later pushed into parts of Alabama, where emergency officials said at least two people were killed at a trailer park near Athens, Alabama.
Arkansas Governor Mike Beebe said at least 15 people had died statewide in the storm.
Nine of the victims on Sunday came from the same street in Vilonia, a town with a population of about 4,100.
State authorities reported that one person was killed in Oklahoma, one in Iowa and another one in Kansas,
The National Weather Service said the threat of tornadoes will last for several days as a strong weather system interacts with a large area of unstable air across the central and southern United States.
According to AP News, The National Weather Service posted tornado watches and warnings around Mississippi, Tennessee, Alabama and Georgia that were in effect through Monday night.
Reuters reported that at least five people were killed on Sunday while some people were injured when a tornado hit a northwest city of Woodward, Oklahoma early on Sunday morning as tornadoes swept across the U.S. Plains states.
Tornadoes were spotted across the Midwest and Plains on Saturday damaging buildings and vehicles in Nebraska, Kansas, Iowa and Oklahoma.
A number of people were reportedly injured in those incidents.
Iowa emergency officials said a large part of the town of Thurman in the western part of the state was destroyed Saturday night but luckily nobody was killed.
Weather forecasters warned that severe storms and more tornadoes touchdown is expected in the region for the rest of the weekend.